How Long Does Vyvanse Last

How Long Does Vyvanse Last


How Long Does Vyvanse Last

Would you believe that in most cases, this Vyvanse medicine is used for treating ADHD or BED?

However, its results of effect are different, when we compare it to its best alternatives – Ritalin and Adderall. Before you take this medication, it’s important to know what Vyvanse exactly is and the manner at which. Being a “pro-drug,” Vyvanse mechanism of action has cool uniqueness which makes it so common after relief several years back, ago.

What is Vyvanse?

What is Vyvanse?

Drug Vyvanse is a medicine used for healing ADHD and Binge-Eating Disorder (BED). Lisdexamfetamine dimesylate is its basic component.

Meanwhile, it becomes active only when you absorb it. No wonder why this drug is a quintessential instance of a “pro-drug.” The point is that lisdexamfetamine gets active only in the blood after metabolization, releasing the parent drug. The process of drug-releasing is much slower, compared to Adderall, as well as the process of absorption goes better.{How Long Does Adderall Stay in Your System}

Lisdexamfetamine directly attacks the Central Nervous System (CNS). As its primary purpose is to stimulate the brain, the CNS gets damaged in various ways and may cause different emotion-based illness.  When Vyvanse start working,  a rapid heart rate may occur.

As a result of the imbalance of emotions, patients suffer from a noticeable lack of appetite. Although Vyvanse for weight loss has no approval, many use it without a doctor’s recommendation. In fact, the digestive organs are harmed by lisdexamfetamine as it may result in problems like constipation, diarrhoea, stomach ache, etc.

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How Delaying Does It Take For Vyvanse To Work?

On average, it requires between 1.5 and 2 hours for Vyvanse to take effect. So, it doesn’t take quite much time for lisdexamfetamine to begin work. The results can take up to 14 hours. When you consider the alternatives to Vyvanse, it is still quite long-lasting. Just as any medicine, Vyvanse does expire, but its impact may not decrease.{how long does Vyvanse last}

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Vyvanse’s duration in the body is around more than three days. Not all individuals should expect the same span. It might vary due to the condition of disease and the dosage recommended. The higher dose of Vyvanse is the longer effects one experiences. Because those who choose to prolong the results of this drug can become addicted. As a result, a doctor may recommend to join an addiction treatment program or go to drug rehabilitation. {How Long Does Adderall Stay in Your System}

How Long Does Vyvanse Last in the System?

A book titled “Workplace Drug Testing”, the length of time that a drug remains in an individual’s system is often calculated or measured by the drug’s half-life (the moment it takes normal metabolic activities to minimize the concentration of the drug by half ). Lisdexamfetamine, the active ingredient in Vyvanse, is without artificial means metabolized into the stimulant dextroamphetamine. Then, Lisdexamfetamine would only be discovered for a very minimal period of time (only a few hours in several cases). Instead, dextroamphetamine, which has a half-life of about 12 hours, would be detectable for longer moments. Dextroamphetamine is an amphetamine-like substance that would show up on most drug tests and diagnoses.

When we base dextroamphetamine on a 12-hour half-life, we expect the drug to be totally removed from the body within 2–3 days.

For general purposes, it can be calculated that it takes about 5.5 half-lives of a particular drug for it to be eliminated from the body. However, several factors can affect the metabolism of any medicine, including the person’s weight and gender, whether or not the medicine was taken in conjunction with other drugs, and how much of the drug was used.

Also, various factors could influence the detectability of the drug in the body system. For example, if an individual were to take several doses of Vyvanse several hours apart, the detectability window should be calculated from the person’s last use of the medicine and not when they began to use the drug.

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How Long Does Adderall Stay in Your System

Generally speaking, Adderall and other alternatives stay for 72 hrs. When we study the urine, its effects last long till roughly 4 to 6 hours. From vast research, Healthwise discovered that  50% of Adderall’s biological activity spans between 10 to 14hrs.

Meanwhile, several factors determine the longevity of Adderall in your system. For example, the Ph Levels in the stomach & urine affect how slow or fast the body depletes the Adderall substances.

Hence, if you take Adderall for a year, for instance, your liver can turn acclimated to it. This would inevitably result in faster elimination. Also, Adderall metabolizes varyingly, depending on the amount of time in your system. When testing for drugs, some tests as well as screen for metabolites.

Screening of Vyvanse Drug

Vyvanse was originally believed to have a lower potential for abuse compared to other prescription stimulant drugs like methylphenidate (e.g., Ritalin). Meanwhile, drug abusers are always passionate to attempt new substances and adapt them to their necessities; therefore, Vyvanse is a potential medicine of abuse.

Also, detecting any drug in a person’s system depends on several factors. Blood tests actually have the shortest detection window. In most cases, Vyvanse would be seen in a person’s blood for up to 8 hours after using it. So, Vyvanse or its metabolites can be expected to be detectable in samples of urine for up to 72 hours and in some cases a little longer. {how long does Vyvanse last}

Meanwhile, Hair analysis distinctively has the longest detection window. Though it can take a few days before a hair sample would test positive for Vyvanse or its sister metabolites. Distinctively, Vyvanse would be detectable in a hair sample for almost a month after the person uses the drug.

Mechanism Of Action Vyvanse Does In A Child’s Body

Metabolism of Vyvanse in children varies from the adult organism. In rare cases, kids with ADHD who uses the medication might undergo the stagnated growth which also affects their adult height. There are three possible action mechanisms on how ADHD drugs like lisdexamfetamine can impact the height of a child. The most apparent one is suppressed appetite. Then, the child organism gets less required microelements and calories that negatively affects physical development. The next mechanism refers to the fact that Vyvanse increases the level of dopamine. {how long does Vyvanse last}

As a result, dopamine may directly cut down growth hormone secretion.

In addition, there are various studies which already studies the adverse influence of stimulants on the growth of cartilage tissue, which in its turn maintain the growth of its bones.

How Lisdexamfetamine Works In Different Body Systems

  • Mechanism Of Action In The Central Nervous System

It’s worthy of note that lisdexamfetamine alters the balance of the brain while increasing the rate of norepinephrine and dopamine. It’s really impossible, for it to have no effect on CNS. Norepinephrine itself is a stimulant, and dopamine is a pleasure substance that occurs naturally. This is why Vyvanse is used for brain stimulation.

If one is suffering from ADHD, they’ll feel a better attention span than before after taking Vyvanse. Lisdexamfetamine also used to control impulsiveness and hyperactivity, as well as binge less frequently (in case of the patients with BED).

  • Mechanism Of Action In The Circulatory System

If one has ever faced any sorts of heart-related problems, they are bound to let their doctors know beforehand. Vyvanse has a rapid and quite problematic circulatory and respiratory negative consequences. Lisdexamfetamine works as a stimulant, so it is advised not to have caffeine while taking it. Vyvanse and Caffeine both increase blood pressure, and their effects can be multiplied. Hence, it is not a suitable drug for a hypertension patient. {how long does Vyvanse last}

  • Mechanism Of Action In The Digestive System

Also, it’s impressive to see how Vyvanse metabolism is just like a biochemical reaction. It is known to be a pro-drug, and any pro-drug gets absorbed easily. Yet, lisdexamfetamine can adversely result in detrimental problems to the digestive organs because of the way it works. These problems are actually secondary conditions of several drugs. Meanwhile, lisdexamfetamine mechanism of action has a long-lasting effect on the digestive organs.

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  • Mechanism Of Action In The Reproductive System

Reproductive organs are actually sensitive to the impacts of various drugs. Lisdexamfetamine is not an exception. Referring to the male reproductive health, Vyvanse mechanism of action can alter spermatogenesis. Erection naturally happens due to testosterone. Normally, a healthy male may expect two to five erections while sleeping, each lasting for 25 to 35 minutes. Vyvanse metabolism can affect the erection cycle. When this happens, a male can experience ejaculatory dysfunction. Asides that, it results in Vyvanse hypersexuality.

On the same vein, a pregnant female should be aware of how lisdexamfetamine impacts. Amphetamines can go through breast milk, so Vyvanse and pregnancy are to be recognized seriously.

Even though human reproduction examinations of lisdexamfetamine have not been performed, the impaired reproduction in animals is confirmed. {How Long Does Adderall Stay in Your System}

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Stay Aware Of How Lisdexamfetamine Works

Vyvanse works like a typical pro-drug. Namely, Vyvanse contains inactive compositions which become active only in the human body. Being an easy absorbed and not frequently taking medication, many users intentionally change to using lisdexamfetamine.


Your health is a vital area of priority, if not the most important to put first in all scales off preference. Vyvanse will always do a wonderful job you’ve been dreaming of. However, as we always say, and we’ll still say, involving your personal or family doctor in any action you want to take as Vyvanse is concerned, is important, as these health specialists understand your body system, more than how you do.

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